, published
Colorado creates a limited natural medicine sales license tied to supervised sessions
Since August 12, 2026, Colorado has let the owners of a licensed healing center hold a new license to sell natural medicine, but only to people taking part in a supervised session there. It is not a dispensary license: nobody can walk in and buy psilocybin to take home, and the same law gave regulators new tools against unlicensed sellers.
From our sister shop, My Mushroom Dispensary. Adults 21+ only.
What happened?
Colorado's Natural Medicine Division, part of the Department of Revenue, lists emergency rule revisions that took effect August 12, 2026 to put in place a new license type, the Limited Regulated Natural Medicine Sales License. New fees took effect on that date too.1 The rules carry out HB26-1325, a bill titled "Natural Medicine." It passed the House 56-7 on May 9, 2026 and the Senate 30-5 on May 13, and the House agreed to the Senate's amendments 59-6, also on May 13.2 The final fiscal note, which reflects the bill as enacted, says it "takes effect on August 12, 2026, assuming no referendum petition is filed."3
The fiscal note describes the license this way: it lets licensees co-locate within a healing center and sell natural medicine "to individuals taking part in an administration session." Legislative staff assumed about 20 of Colorado's 40 healing center licensees at the time would apply.3 The rule text on file with the Colorado Secretary of State says the license must sit at the same licensed premises as a healing center with common ownership.4
The same law sharpened enforcement. According to the fiscal note, it lets the division's director "issue an order to cease and desist" after an investigation finds a violation, says state law does not permit using "harm reduction services or support services to conduct sales of natural medicines," and bars advertising natural medicine or its products.3
As of October 30, 2026, the division listed 47 approved healing center licenses (12 standard and 35 micro). Its page gives no count of limited sales licenses issued.1
What does it mean if you're looking for a mushroom dispensary?
Colorado still has no walk-in psilocybin dispensary. The only lawful purchase is inside a licensed healing center, during a supervised session with a licensed facilitator, by an adult whose age, 21 or older, the facilitator has verified.5 The new license adds a seller inside the center, not a new group of buyers, and the fiscal note describes no take-home, public or mail-order sales. Our guide to licensed psilocybin centers explains how sessions work and links the state's official lookup.
Colorado is unusual in one more way. Adults 21 and older may possess and share natural medicine for personal use without payment under state law, but the statute says that does not allow anyone to "dispense, sell, or distribute" it for remuneration outside the licensed system.6 Psilocybin is still a Schedule I drug under federal law in every state. That is why a Colorado shop or "support service" that charges for mushrooms is unlicensed, and why the new cease-and-desist power matters. Our Denver guide covers the storefronts and the letters regulators have sent them, and the dated record is in the register's entry for August 12, 2026 and its note on the division's May 1, 2026 bulletin on prohibited sales.
What happens next?
The division is writing permanent rules for HB26-1325. Its final rulemaking hearing is set for Wednesday, November 4, 2026, at 9:30 a.m., in Lakewood and online, and written comments are due by 5 p.m. that day. Topics include temporary premises permits, limited sales licenses and a process for waiving or adjusting testing requirements.7 We'll update this post when the permanent rules are adopted or the division publishes a count of limited sales licenses.
Sources
- Natural Medicine Division home page: rules, fees and approved licenses as of October 30, 2026, Colorado Department of Revenue, accessed November 2, 2026.
- HB26-1325, Natural Medicine: bill history and votes, Colorado General Assembly, accessed November 2, 2026.
- HB 26-1325 Final Fiscal Note, Colorado Legislative Council Staff, July 9, 2026.
- 1 CCR 213-1, Regulated Natural Medicine Rules (version 12671), Colorado Secretary of State, accessed November 2, 2026.
- C.R.S. 44-50-401, healing center license, Colorado Revised Statutes via Colorado.Public.Law, current through fall 2025.
- C.R.S. 18-18-434, natural medicine personal use, Colorado Revised Statutes via Colorado.Public.Law, current through fall 2025.
- Rulemaking: HB26-1325 permanent rules, hearing and comment deadline, Colorado Natural Medicine Division, accessed November 2, 2026.
Keep reading
Where can you take psilocybin legally in the US?Oregon service centers, Colorado healing centers, New Mexico, two hospital pilots and trials: counts, rules and official lookups.
Is there a mushroom dispensary in Denver?Colorado licenses healing centers, not dispensaries. What adults may do, the new sales license, and Denver's unlicensed shops.
Seven legal claims mushroom dispensaries make, and what courts saidDecriminalized, gift, church, membership, Amanita, spores, licensed: each claim against the statute and the rulings.
Kept by the Dispensary Register editors. Facts on this page link to the sources they come from. Spot an error? Tell us and we'll correct it in the open, as our editorial standards describe. Psychedelic Mushroom Dispensary is a reference site, not a store. It is published by the people who run My Mushroom Dispensary, an online shop. We sell no advertising and nothing on this site.