Where can you take psilocybin legally in the US?

Where can you take psilocybin legally?

In two states. Oregon licenses psilocybin service centers and Colorado licenses healing centers, and in both an adult 21 or older takes psilocybin in a supervised session with a licensed facilitator, normally at the center, and leaves with nothing.¹⁶

That is the whole of legal retail access in the US as of November 2, 2026. Neither state allows walk-in purchase to take home, delivery or shipping, and both programs exist under state law only: psilocybin is still a Schedule I drug federally (see are mushroom dispensaries legal). Beyond the two programs, the routes are narrow: New Mexico's medical program once it opens, hospital pilots in New Jersey and Utah, and federally authorized clinical trials.

How do Oregon's psilocybin service centers work?

Oregon voters created the program with Measure 109 in 2020, and the Oregon Health Authority licenses it under ORS chapter 475A. The core rule is ORS 475A.498: a client "may purchase, possess, and consume a psilocybin product: (1) Only at a psilocybin service center; and (2) Only under the supervision of a psilocybin service facilitator." Administration sessions must be held at a service center, sales "must be restricted to the premises for which the license has been issued," and licensees may not sell to anyone under 21.¹

The program is small and has shrunk. As of July 23, 2026, the health authority counted²:

• 20 licensed service centers (39 licensed at some point since the start), with "over 33%" having surrendered or not renewed their licenses
• 379 licensed facilitators (641 all-time), 7 manufacturers and 1 testing laboratory
• 46,273 psilocybin products sold to clients from January 1, 2023 to July 23, 2026, with no product safety recalls and 32 reports of emergency services being contacted
• 5,935 clients served in 2025

Cities and counties can ask voters to ban service centers within their borders (ORS 475A.718),¹ and Redmond and Reedsport vote on keeping them out on the November 3, 2026 ballot. More on Oregon's history, including the 2024 possession law, is on our Oregon page.

How do Colorado's healing centers work?

Colorado voters passed Proposition 122, the Natural Medicine Health Act, in November 2022. The Department of Revenue's Natural Medicine Division licenses the businesses and began taking applications on December 31, 2024; facilitators are licensed separately by the Department of Regulatory Agencies.⁵

A healing center license "may be issued only to a person that employs or contracts with a facilitator," and the facilitator "shall verify that the participant is twenty-one years of age or older."⁶ Sessions take place at a healing center or another location the law allows.⁸ As of October 30, 2026, the division listed these approved licenses⁵:

• 47 healing centers: 12 standard and 35 micro
• 15 cultivation facilities, 8 product manufacturers and 1 testing facility
• 129 owner licenses and 211 handler licenses

The limited sales license. Since August 12, 2026, a healing center's owner can hold a Limited Regulated Natural Medicine Sales License, which "must be at the same Licensed Premises as a Healing Center with Common Ownership."⁸ It lets the licensee sell "to individuals taking part in an administration session." The legislature's fiscal analysis assumed about 20 of 40 healing center licensees would apply.⁷ The division's page showed no count of these licenses as of November 2, 2026.⁵ It is a point of sale inside a center, not a store (see our news report).

Colorado also lets adults 21 and older possess and share psilocybin "without remuneration" outside any center. That is a personal-use right, not a place to buy: the same law bars selling it outside the licensed system.⁹ More on Denver is on our Denver page.

What happens in a supervised session?

Details differ by state and center, but the shape is the same in both programs:

1. Screening before the session. In Oregon, each client completes the health authority's client information form, which the facilitator reviews. Some answers rule a person out: anyone who took lithium in the last 30 days, has been diagnosed with or treated for active psychosis, or is having thoughts of harming themselves or others "may not participate in an administration session." The facilitator also tells pregnant and breastfeeding clients that the risks "are unknown."³
2. The session itself, on site. The client takes the product with a licensed facilitator present, at the licensed premises (Colorado allows some sessions at other approved locations).¹⁸
3. Leaving with nothing. Neither state allows a client to take psilocybin home. Oregon limits a client's purchase and possession to the service center, and Colorado's rules require any product a participant doesn't consume to be destroyed or locked away at the end of the session.¹⁸

Some people should not take psilocybin at all, even in a center. Our help page covers who research excludes and where to call if something goes wrong.

When will New Mexico's medical program open?

Not yet. New Mexico's Medical Psilocybin Act (SB 219) took effect June 20, 2025.¹⁰ It covers qualified patients with major treatment-resistant depression, post-traumatic stress disorder, substance use disorders, end-of-life care, or other conditions the health department approves, and it protects patients "taking psilocybin in an approved setting." The law gives the department until December 31, 2027 to start the program.¹¹ The department says it is "set to be implemented by December 31, 2026."¹⁰

The rule that would enroll patients and certify clinicians, facilitators, "healing centers and other approved locations" (7.35.3 NMAC) went to a public hearing on October 2, 2026.¹² No adoption had been announced as of November 2, 2026. When the program runs, it will be supervised medical use, not a store or a card that works anywhere else.

What are the New Jersey and Utah pilots?

New Jersey. P.L.2025, c.296, approved January 20, 2026, creates a Psilocybin Behavioral Health Access and Therapy Pilot Program at three hospitals, one each in the northern, central and southern regions, to support psilocybin research that complies with FDA and DEA rules.¹³ It has no retail or take-home provisions. Which hospitals were selected had not been announced in the sources we checked.

Utah. A 2024 law (SB 266) that became law without the governor's signature on March 21, 2024 lets qualifying health systems run a tightly regulated program for their own patients.¹⁴ Participants cannot take the drugs home.¹⁵

Both are patient programs inside medical systems. There is no public sign-up and no storefront.

Can I join a psilocybin clinical trial?

Yes, if you qualify for one. Outside the state programs, the only legal way to receive psilocybin in the US is as an enrolled participant in a federally authorized clinical trial. Trials have their own screening and exclusion rules. Federal trials are listed on ClinicalTrials.gov, the National Library of Medicine's registry.

No psilocybin medicine was FDA-approved as of November 2, 2026. Compass Pathways said in August 2026 that it expected to finish its new drug application for COMP360, its psilocybin drug candidate, in the fourth quarter of 2026, with a commercial launch expected in the first half of 2027, "subject to FDA approval and following Drug Enforcement Administration (DEA) rescheduling."¹⁶ If approved, it would be a prescription treatment given under medical supervision, not a product sold over a counter.

How do I check that a center is licensed?

Use the states' own lookups, not a business's word:

• Oregon: the psilocybin license directory and the license status lookup. Listing in the directory is optional, so the health authority says it "is not a comprehensive list of OPS licensees."⁴ General information is on the Oregon Psilocybin Services page.
• Colorado: the Natural Medicine license verification and the division's page on accessing regulated natural medicine.
• New Mexico: the health department's Medical Psilocybin Program page, for updates on when patients can enroll.

Costs vary from center to center, and this site doesn't publish prices. Ask the center directly and check the program pages above. Any business that offers take-home sales, delivery or shipping is not operating under either state's license.